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O cientista Bruce Ivins do Anthrax estêve para beneficiar-se de um pânico

Sábado, agosto 2o, 2008
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O suspeito nos enviamentos mortais, que se mataram himself esta semana como o FBI fechou-se dentro, poderia ter coletado royalties da patente em uma vacina do anthrax.
Por David Willman, Los Angeles cronometra o escritor da equipe de funcionários 
Agosto 2, 2008 
Bruce E. Ivins, cientista do biodefense do governo ligado aos enviamentos mortais do anthrax de 2001, estados para ganhar financeira da despesa federal maciça no aftermath medo-enchido daquelas matanças, os tempos de Los Angeles aprendeu.

Ivins é alistado como um co-inventor em duas patentes para uma vacina genetically projetada do anthrax, registros federais mostra. Separada, Ivins é alistado também como um co-inventor em uma aplicação para patentear um aditivo para várias vacinas do biodefense.

Ivins, 62, morridos terça-feira em um suicide aparente em Maryland. As autoridades federais tinham informado seu advogado que as cargas criminal relacionadas aos enviamentos estariam arquivadas.

Como um co-inventor de uma vacina nova do anthrax, Ivins era entre aqueles na linha para coletar royalties da patente se o produto viesse introduzir no mercado, de acordo com um familiar do executivo com a matéria.

O produto languished em prateleiras do laboratório até o Sept. 11 ataques e os enviamentos do anthrax, depois do qual os oficiais federais competiram para stockpile vacinas e antidotes de encontro ao terrorismo biológico potencial.

Uma companhia da biotecnologia da Francisco-área do San, VaxGen, ganhou um contrato federal worth $877.5 milhões para fornecer grupos da vacina nova. O contrato era concedido primeiramente sob a legislação promovida pelo presidente Bush, chamado Projeto BioShield.

Um executivo que era familiar com a matéria disse que, como uma condição de seu comprar a vacina do exército, VaxGen teve concorda aos rendimentos venda-relacionados da parte com os inventores.

“Alguma proporção seria compartilhada com os inventores,” disse o executivo, que falou anonymously por causa do confidentiality contractual. “Ivins estaria para fazer dez dos milhares dos dólares, mas não dos milhões.”

Dois anos depois que o contrato foi concedido a VaxGen, o pact foi terminado quando a companhia não poderia entregar seus grupos na programação. A terminação significou que VaxGen não era pago, nem eram Ivins e seus co-inventores.

Ivins foi alistado também como um de dois inventores de um outro produto biodefense-relacionado que ganhasse o sponsorship federal.

De acordo com sua aplicação ainda-pendente para uns ESTADOS UNIDOS. patent, the inventors hoped the additive would bolster certain vaccines’ capacity to prevent infections “from bioterrorism agents.”

From December 2002 to December 2003, the Pentagon’s Defense Advanced Research Projects Agency committed $12 million for additional testing of the experimental additive. That research money was designated for Coley Pharmaceutical Group, which was developing the additive. The company was acquired last fall by Pfizer Corp.

Samuel C. Miller, a Georgetown Law Center professor who is a patent-law expert, said that the extent to which Ivins stood to gain from the two issued patents or the one that remains pending hinges on the terms of the related contracts.

“It will depend on the business arrangements that are in place,” Miller said.

On Friday, colleagues and critics of Ivins pondered the mystery within the mystery: If Ivins did it, why?

One former senior official with Ivins’ employer, the U.S. Army Medical Research Institute of Infectious Diseases, whom the FBI questioned at length about Ivins, said he believed his former colleague wanted more attention — and resources — shifted to biological defense.

“It had to have been a motive,” said the former official, who suspects that Ivins was the culprit. “I don’t think he ever intended to kill anybody. He just wanted to prove ‘Look, this is possible.’ He probably had no clue that it would aerosolize through those envelopes and kill those postal workers.”

Of the five people killed by the mailings, two worked for the U.S. Postal Service in the Washington, D.C., area; one was a photo editor in Palm Beach County, Fla.; another was a hospital supply provider in New York City; and the last known victim was a 94-year-old woman in Connecticut.

Several letters were addressed to prominent people — two U.S. senators and NBC news anchor Tom Brokaw, for example.

For nearly 30 years, Ivins served far from the limelight, a PhD microbiologist who drew a civil servant’s pay while handling some of the most deadly pathogens on Earth — live spores of anthrax.

The deadly mailings of anthrax-tainted envelopes transported Ivins from the backwater of government scientific research at Ft. Detrick, Md., to the center of the nation’s fledgling war on terrorism. It also spurred multibillion-dollar national security initiatives.

Ivins was thrust into the federal investigation of the mailings as well. He helped the FBI analyze anthrax recovered from a letter addressed to then-Senate Majority Leader Tom Daschle (D-S.D.).

He also played a lead role in helping a private company, BioPort, win regulatory approval to continue making the vaccine required for U.S. service personnel deployed to Iraq, Afghanistan and other regions.

From 2000 to early 2002, Ivins and two colleagues from USAMRIID helped BioPort resolve problems related to the potency of the vaccine. Because of those and other manufacturing difficulties, production had been suspended. The efforts of Ivins and his colleagues helped BioPort win FDA approval to resume production.

At a Pentagon ceremony on March 14, 2003, Ivins and two colleagues from USAMRIID were bestowed the Decoration of Exceptional Civilian Service, the highest honor given to nonmilitary employees of the Defense Department.

“Awards are nice,” Ivins said in accepting the honor. “But the real satisfaction is knowing the vaccine is back on line.”

The Times sought earlier this year to obtain annual financial disclosure statements filed by Ivins with his employer. USAMRIID spokeswoman Caree Vander Linden said last month that Ivins had filed financial reports exempt from disclosure under the Freedom of Information Act.

Ivins’ apparent suicide and the Justice Department’s decision to bring criminal charges against him were first reported Thursday night by The Times. On Friday, Ivins’ lawyer, Paul F. Kemp, defended his client and said that Ivins had cooperated fully with the FBI.

“We assert his innocence in these killings, and would have established that at trial,” Kemp said, implicitly confirming that Ivins had been about to be formally charged. “The relentless pressure of accusation and innuendo takes its toll in different ways on different people. . . . In Dr. Ivins’ case, it led to his untimely death.”

Kemp did not respond to telephone calls and e-mails for this article.

Times researcher Janet Lundblad contributed to this report.


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