{"id":45850,"date":"2013-06-27T18:30:37","date_gmt":"2013-06-27T17:30:37","guid":{"rendered":"http:\/\/rinf.com\/alt-news\/breaking-news\/potential-adverse-cardiovascular-effects-from-excessive-endurance-exercise\/45850\/"},"modified":"2013-06-27T18:30:37","modified_gmt":"2013-06-27T17:30:37","slug":"potential-adverse-cardiovascular-effects-from-excessive-endurance-exercise","status":"publish","type":"post","link":"http:\/\/rinf.com\/alt-news\/breaking-news\/potential-adverse-cardiovascular-effects-from-excessive-endurance-exercise\/","title":{"rendered":"Potential adverse cardiovascular effects from excessive endurance exercise."},"content":{"rendered":"<div class=\"field field-type-text article-free\">\n<p>Article Publish Status: FREE<\/p>\n<\/div>\n<div class=\"field field-type-text field-field-scientific-purpose\">\n<p>Abstract Title: <\/p>\n<div class=\"field-items\">\n<div class=\"field-item odd\">\n<p>Potential adverse cardiovascular effects from excessive endurance exercise.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"field field-type-text field-field-pmid\">\n<p>Abstract Source: <\/p>\n<div class=\"field-items\">\n<div class=\"field-item odd\">\n<p>Mayo Clin Proc. 2012 Jun ;87(6):587-95. PMID: <a target=\"_blank\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22677079\" rel=\"nofollow\">22677079<\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"field field-type-text field-field-abstract_author\">\n<p>Abstract Author(s): <\/p>\n<div class=\"field-items\">\n<div class=\"field-item odd\">\n<p>James H O&#8217;Keefe, Harshal R Patil, Carl J Lavie, Anthony Magalski, Robert A Vogel, Peter A McCullough<\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"field field-type-text field-field-article_affiliation\">\n<p>Article Affiliation: <\/p>\n<div class=\"field-items\">\n<div class=\"field-item odd\">\n<p>Mid America Heart Institute of Saint Luke&#8217;s Hospital of Kansas City, MO, USA. jokeefe@saint-lukes.org<\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"field field-type-text field-field-full-citation\">\n<p>Abstract: <\/p>\n<div class=\"field-items\">\n<div class=\"field-item odd\">\n<p>A routine of regular exercise is highly effective for prevention and treatment of many common chronic diseases and improves cardiovascular (CV) health and longevity. However, long-term excessive endurance exercise may induce pathologic structural remodeling of the heart and large arteries. Emerging data suggest that chronic training for and competing in extreme endurance events such as marathons, ultramarathons, ironman distance triathlons, and very long distance bicycle races, can cause transient acute volume overload of the atria and right ventricle, with transient reductions in right ventricular ejection fraction and elevations of cardiac biomarkers, all of which return to normal within 1 week. Over months to years of repetitive injury, this process, in some individuals, may lead to patchy myocardial fibrosis, particularly in the atria, interventricular septum, and right ventricle, creating a substrate for atrial and ventricular arrhythmias. Additionally, long-term excessive sustained exercise may be associated with coronary artery calcification, diastolic dysfunction, and large-artery wall stiffening. However, this concept is still hypothetical and there is some inconsistency in the reported findings. Furthermore, lifelong vigorous exercisers generally have low mortality rates and excellent functional capacity. Notwithstanding, the hypothesis that long-term excessive endurance exercise may induce adverse CV remodeling warrants further investigation to identify at-risk individuals and formulate physical fitness regimens for conferring optimal CV health and longevity.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<p>This article originally appeared on: <a href=\"http:\/\/www.greenmedinfo.com\/article\/potential-adverse-cardiovascular-effects-excessive-endurance-exercise\" target=\"_blank\" title=\"Potential adverse cardiovascular effects from excessive endurance exercise.\">Green Med Info<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Article Publish Status: FREE Abstract Title: Potential adverse cardiovascular effects from excessive endurance exercise. Abstract Source: Mayo Clin Proc. 2012 Jun ;87(6):587-95. PMID: 22677079 Abstract Author(s): James H O&#8217;Keefe, Harshal R Patil, Carl J Lavie, Anthony Magalski, Robert A Vogel, Peter A McCullough Article Affiliation: Mid America Heart Institute of Saint Luke&#8217;s Hospital of Kansas [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[487],"tags":[],"class_list":{"0":"post-45850","1":"post","2":"type-post","3":"status-publish","4":"format-standard","6":"category-breaking-news"},"_links":{"self":[{"href":"http:\/\/rinf.com\/alt-news\/wp-json\/wp\/v2\/posts\/45850","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/rinf.com\/alt-news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/rinf.com\/alt-news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/rinf.com\/alt-news\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/rinf.com\/alt-news\/wp-json\/wp\/v2\/comments?post=45850"}],"version-history":[{"count":0,"href":"http:\/\/rinf.com\/alt-news\/wp-json\/wp\/v2\/posts\/45850\/revisions"}],"wp:attachment":[{"href":"http:\/\/rinf.com\/alt-news\/wp-json\/wp\/v2\/media?parent=45850"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/rinf.com\/alt-news\/wp-json\/wp\/v2\/categories?post=45850"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/rinf.com\/alt-news\/wp-json\/wp\/v2\/tags?post=45850"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}