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星期五, 2007年8月10日

利他灵: ADHD药物也许影响开发的脑子

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利他灵-被给大约5百万个年轻美国人诊断与ADHD (关注性赤字,活动过度的混乱) -可以影响开发的脑子。

利他灵(哌醋甲酯)是兴奋剂相似与安非他明和可卡因和它似乎有一个似是而非的作用在ADHD孩子,并且镇定他们。

But it may do so at a price, new research suggests.  The new study, which monitored the effect of the drug on the brains of rats, found that it altered areas of the brain related to executive functioning, addiction and appetite, social relationships and stress.

The rats recovered the longer they were off the drug, researchers noticed.

Although there’s often no direct correlation between the effects on animals and humans, the rats did respond in a similar way when they were first given Ritalin.  They lost weight, which often happens in children who first take the drug.

The fact that the rats soon regained their healthy mental capacities suggests the drug should be taken over a short period of time rather than for years as currently happens, the researchers say.

(Source: Journal of Neuroscience, 2007; 27: 7196-7207).

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