Debra Kain对此， kain

Smoked cannabis eased pain induced in healthy volunteers, according to a study by researchers at the University of California, San Diego (UCSD) Center for Medical Cannabis Research (CMCR.) However, the researchers found that less may be more.吸食大麻缓解疼痛致在健康志愿者，根据一项研究，研究人员在加州大学圣迭戈分校（ UCSD的）中心，为医疗大麻研究所（ cmcr. ）不过，研究者发现，那么可能会有更多。

In the placebo controlled study of 15 subjects, a low dose of cannabis showed no effect, a medium dose provided moderate pain relief, and a high dose increased the pain response.在安慰剂对照研究的15个课题，低剂量的大麻显示，没有任何影响，中等剂量提供中度疼痛救济金，高剂量时增加了疼痛反应。 The results suggest a “therapeutic window” for cannabis analgesia, according to lead researcher Mark Wallace, MD, professor of anesthesiology at UCSD School of Medicine and Program Director for the UCSD Center for Pain Medicine.结果表明， "治疗窗" ，为大麻止痛，据率先研究员马克华莱士医学博士，教授，麻醉学，在加州大学圣地亚哥分校医学院和项目总监为UCSD的中心止痛药。

The paper, to be published in the November issue of the journal Anesthesiology, is the second published study out of the CMCR.文件，将刊登在11月份出版的杂志上的麻醉，是第二个发表研究出来的cmcr 。 Headquartered at UCSD, the CMCR is collaboration between UCSD and UC San Francisco that was funded by a state-funded initiative in 1999 to rigorously study the safety and efficacy of medicinal cannabis in treating diseases.总部设在加州大学圣地亚哥分校， cmcr是之间的协作加州大学圣地亚哥分校和加州大学旧金山报告是由国家资助的倡议，在1999年以严谨研究的安全性和疗效的药用大麻在治疗疾病。

The study used capsaicin, an alkaloid derived from hot chili peppers that is an irritant to the skin, to mimic the type of neuropathic pain experienced by patients with HIV/AIDS, diabetes or shingles – brief, intense pain following by a longer-lasting secondary pain.这项研究使用的辣椒素，生物碱来自炎热辣椒这是一项刺激性皮肤，可以模仿型的神经性疼痛经历的艾滋病毒/艾滋病病人，患有糖尿病或带状疱疹-简言之，剧烈疼痛，紧接着较持久中学疼痛。 The subjects were healthy volunteers who inhaled either medical cannabis or a placebo after pain was induced.受试者健康志愿者因吸入或者医疗大麻或安慰剂后，疼痛所致。 The marijuana cigarettes were formulated under NIH supervision to contain either zero, two, four or eight percent delta-9-tetrahydrocannabinol (THC.)大麻香烟下形成的美国国家卫生署监督，以遏制要么是零，二，四或八％三角洲- 9 -四氢大麻酚（ thc. ）

“Subjects reported a decrease in pain at the medium dose, and there was also a significant correlation between plasma levels of THC, the active ingredient in cannabis, and decreased pain,” said Igor Grant, MD, FRCP(C), professor and Executive Vice-Chair of the Department of Psychiatry, the director of the CMCR. "课题报告，减少疼痛，在中等剂量，也有显着相关的血浆水平THC等活性成分大麻，并减少疼痛，说： "伊戈尔补助，海事处， frcp （三） ，教授及行政人员副主任，该部的精神病，总的cmcr 。 “Interestingly, the analgesic effect wasn’t immediate; it took about 45 minutes for the cannabis to have an impact on the pain,” he said. "有趣的是，镇痛效果不是即时，它花了大约45分钟，为大麻有一个影响，对疼痛的， "他说。

The results, showing a medium-dose (4% THC by weight) of cannabis to be an effective analgesic, converged with results from the CMCR’s first published study, a paper by UCSF researcher Donald Abrams, MD published in the journal Neurology in February 2007.研究结果显示，一个中等剂量（ 4 ％货柜码头处理费按重量计算）的大麻是一种有效的镇痛，融合的结果，从cmcr的首次发表研究报告，一份文件！三藩市加州大学的研究员唐纳德艾布拉姆斯医学博士发表在杂志上，在神经内科2007年2月。 In that randomized placebo-controlled trial, patients smoking the same dose of cannabis experienced a 34% reduction in HIV-associated sensory neuropathy pain—twice the rate experienced by patients receiving a placebo.在这方面，随机，安慰剂对照试验，病人吸烟同样剂量的大麻经历了34 ％ ，减少艾滋病毒相关性感觉神经病变疼痛增长率的两倍，由经验丰富的病人接受安慰剂。

“This study helps to build a case that cannabis does have therapeutic value at a medium-dose level,” said Grant. "这项研究有助于建立一宗大麻是否有治疗价值，在中等剂量水平，说： "补助金。 “It also suggests that higher doses aren’t necessarily better in certain situations – something also observed with other medications, such as antidepressants.” "这也表明，较高剂量的不一定是好，在某些情况下-东西还观察到，与其他药物，如抗抑郁药" 。

The researchers stated that more and larger studies need to be conducted to measure the efficacy of cannabis, noting that medical marijuana could play an important role in treating patients who don’t respond well to the usual pain relievers or can’t tolerate drugs such as ibuprofen or opioids used for severe pain.研究人员指出，更多和更大的研究，需要进行衡量疗效的大麻，并注意到药用大麻可发挥重要作用，在治疗病人，他们不回应，以及以一般止痛药或不能忍受药物如布洛芬或阿片类药物用于重度疼痛。

“The results of this study might help guide others doing clinical research into pain management,” said Wallace. "这项研究结果或许有助于引导别人做临床研究，疼痛管理，说： "华莱士。

### ＃ ＃ ＃

Additional contributors to the study include Gery Schulteis, Ph.D., UCSD Department of Anesthesiology; J. Hampton Atkinson, MD, professor, and Deborah Lazzaretto, MS, UCSD HIV Neurobehavioral Research Center; Ian Abramson, Ph.D., UCSD Department of Mathematics and HIV Neurobehavioral Research Center; Tanya Wolfson, MA, UCSD Department of Family and Preventive Medicine; and Heather Bentley and Ben Gouaux, UCSD Center for Medicinal Cannabis Research.额外供款，以研究包括gery schulteis ，博士，加州大学圣地亚哥分校部麻醉学的J.汉普顿阿特金森博士，教授，并德博拉lazzaretto ，质谱， UCSD的艾滋病毒神经研究中心;伊恩Abramson在博士，加州大学圣地亚哥分校部数学与艾滋病毒神经研究中心;联赛沃尔夫森，硕士，加州大学圣地亚哥分校部家庭和预防医学;和石南宾利和Ben gouaux ， UCSD的中心药用大麻的研究。

Comment on 'Cannabis proven effective in treating neuropathic pain' : 评论'大麻被证明能有效治疗神经性疼痛' ：

RSS 的RSS TrackBack URL 跟踪 RUI

Related News: 相关新闻：